darcysesko - I think a horizontal run would be much easier to do since I've seen with my own eyes a vertical run for at least the same run. The macerator flush technology provides a number of advantages. Firstly, the toilet and the waste tank can be placed separately from each other. The tank is completely emptied without problems. Also, a macerator toilet prevents problems and simplifies waste disposal. As for the pipe, I think the 1 inch would be the perfect choice - https://sumppumpadvisor.com/best-sump-pump-check-valve/.